Check for newest update information (Update on 20200918)

Sep 18th, 2020

[Biomarker Evaluation] Add 2 new ICB Cohorts.
  • ICB Cohort: Zhao2019_PD1_Glioblastoma_RNASeq,Braun2020_PD1_Kidney_RNASeq_Clear

Feb 26th, 2020

[Publication] Our latest paper was published on Genome Medicine.

Feb 6th, 2020

[Offline Version] We provide an offline version of response prediction module now (with source code). Please See here in detail.

Dec 1nd, 2019

[Regulator Prioritization] Add 3 new CRISPR Screen datasets and 3 ICB cohorts.
  • CRISPR Screen: Pech 2019, Freeman 2019, Vredevoogd 2019
  • ICB Cohort: Gide2019, Lauss2017_ACT, Nathanson2017_CTLA4

Nov 20th, 2019

[Biomarker Evaluation] Add 6 new ICB Cohorts.
  • ICB Cohort: Gide2019_Melanoma_RNASeq, McDermott2018_Kidney_Clear_RNASeq, Kim2018_Gastric_RNASeq, Lauss2017_Melanoma_RNASeq, Nathanson2017_Melanoma_RNASeq, Chen2016_Melanoma_Nanostring

May 2nd, 2019

[Prediction Module] Change the MSI model to hg38 version.
  • MSI Score: Predictive Microsatellite status based on gene expression profile

Feb 19th, 2019

[Prediction Module] Added one additional columns
  • MSI Score: Predictive Microsatellite status based on gene expression profile

August 20th, 2018

[Prediction Module] Added two additional columns
  • No benefits: This column shows the predicted non-responders with high confidence by the combination of TIDE and IFNG signature
  • IFNG: Interferon gamma (IFNγ) response biomarkers of 6 genes including IFNG, STAT1, IDO1, CXCL10, CXCL9, and HLA-DRA

September 10th, 2018

T-cell dysfunction and exclusion scores for all samples
  • T-cell exclusion scores: In the result page of Predict Response module, three new columns were added to show the sample-level correlation with immune-suppressive cell types (i.e., CAF, TAM M2, MDSC).
  • sample scores: We added the T-cell dysfunction and exclusion scores computed for all collected samples in the download page "Analysis results" section.

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