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Source code to compute T-cell dysfunction scores.

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Available under the GNU Public License Version 3. It has been tested on Linux and Mac OS X.

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Analysis results

You can download our analysis results on TCGA, PRECOG and METABRIC cohorts.

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Available under the GNU Public License Version 3.

Immunotherapy trial studies

Study Data Public Available Access-controlled
Transcriptome Clinical Outcome Response Outcome
Braun et al., Nat Medicine 2020 Paper Supplementary Table Paper Supplementary Table Paper Supplementary Table
Zhao et al., Nat Medicine 2019 PRJNA482620 Paper Supplementary Table Paper Supplementary Table
Liu et al., Nat Medicine 2019 phs000452.v3.p1 Paper Supplementary Table Paper Supplementary Table dbGaP
Gide et al., Cancer Cell 2019 PRJEB23709 Paper Supplementary Table (1)
Paper Supplementary Table (2)
Paper Supplementary Table (1)
Paper Supplementary Table (2)
Cristescu et al., Science 2018 Only expression of a few genes (n=29) available Require to submit an access application Require to submit an access application
Rodig et al.,  Sci Transl Med 2018 Only released processed data related to the study. Only released processed data related to the study. Only released processed data related to the study.
McDermott et al., Nat Medicine 2018 EGAD00001004183 No information. EGAD00001004183 EGA
Kim et al., Nat Medicine 2018 PRJEB25780 No information. Paper Supplementary File
Mariathasan et al., Nature 2018 EGAS00001002556 EGAS00001002556 EGAS00001002556 EGA
Miao et al., Science 2018 phs001493.v1.p1 Paper Supplementary Table (1)
Paper Supplementary Table (2)
Paper Supplementary Table (1)
Paper Supplementary Table (2)
dbGaP
Riaz et al., Cell 2017 GSE91061 Paper Supplementary Table Paper Supplementary Table
Nathanson et al., Cancer Immunol Res 2017 Paper Supplementary Table Paper Supplementary Table Paper Supplementary Table
Prat et al., Cancer Res 2017 GSE93157 Paper Supplementary Table Paper Supplementary Table
Ayers et al., J Clin Invest 2017 Do Not Provide Do Not Provide Do Not Provide
Lauss et al., Nat Commun 2017 GSE100797 Paper Supplementary Table Paper Supplementary Table
Hugo et al., Cell 2016 GSE78220 Paper Supplementary Table Paper Supplementary Table
Chen et al., Cancer Discov 2016 Paper Supplementary Table No information. Paper Supplementary Table
Van Allen et al., Science 2015 phs000452.v2.p1 Paper Supplementary Table Paper Supplementary Table dbGaP

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